As mentioned in the "Getting Started" section the real power of Screem comes when you are working on a project rather than individual files. So just how do you go about creating a project?

The Site Druid window will then be displayed, and guide you through the necessary steps to create a new site.

This will have the same effect as if you had used the menu.
You can open any existing folder and Screem will create a site from this. see the following section on Opening an existing site

This method will display the file selector allowing you to choose a folder. This folder will then be opened as a site.

This method will display a dialog allowing you to enter a URL to where the site is located. This could be and FTP site, a WebDAV share, an SFTP connect, or any other method that is supported by GNOME

As mention previously if there is no Screem project file to be found in the folder the site settings dialog will be displayed for initial options to be specified.